Ending Aging

Ending Aging presents a comprehensive argument that aging should be understood as a medical condition rather than an inevitable aspect of life. De Grey outlines seven major categories of age-related damage at the cellular and molecular level, and proposes specific biotechnological interventions—collectively termed SENS (Strategies for Engineered Negligible Senescence)—to repair or prevent each type of damage.

The book combines scientific exposition with advocacy, drawing on de Grey's background in computer science and his work at the University of Cambridge. It argues that rejuvenation biotechnology is not merely speculative but achievable within decades if adequate research funding and focus are directed toward the field. De Grey contends that the primary barrier is not scientific impossibility but rather institutional inertia and insufficient prioritization of aging research.

Published in 2007, the work became influential in the emerging longevity and life extension movement, helping to establish de Grey as a prominent public intellectual in debates about human lifespan extension. The book's arguments have been both celebrated by transhumanists and life extension advocates and critiqued by mainstream gerontologists for overstating near-term feasibility.